MolNFT v1 · #156716 · protein

Crystal structure of zebrafish VPS26A

6MD5 · Vacuolar protein sorting-associated protein 26A: “Crystal structure of zebrafish VPS26A”. X-ray diffraction, 3 pockets (best druggability 0.53). MolNFT v1 #156716 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MD5
Type: protein
Length: 273 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Vacuolar protein sorting-associated protein 26A
UniProt: Q6TNP8
Pockets: 3 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 59% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vacuolar protein sorting-associated protein 26A	protein	273	3% helix, 59% strand	Q6TNP8

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	243	0.53	0.76	32	empty
2	50	0.42	0.83	14	empty
3	82	0.41	0.78	18	empty

Compared structures

6MD5 · Crystal structure of zebrafish Vps26A · the same entry in another collection · chain A against A, TM-score 1.00
Q6TNP8 · AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 26A… · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6TNP8
Elsewhere: RCSB PDB 6MD5 · PDBe 6MD5 · UniProt Q6TNP8

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