MolNFT v1 · #156687 · protein

Crystal structure of ppra filament from deinococcus radiodurans

6MC6 · DNA repair protein ppra: “Crystal structure of ppra filament from deinococcus radiodurans”. X-ray diffraction, 6 pockets (best druggability 0.48). MolNFT v1 #156687 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MC6
Type: protein
Length: 540 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA repair protein ppra
UniProt: O32504
Pockets: 6 · best druggability 0.48

Structure

x-ray diffraction · 2 distinct chains · 51% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA repair protein ppra	protein	270	51% helix, 17% strand	O32504
B	DNA repair protein ppra	protein	270	51% helix, 17% strand	O32504

Pockets

6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	77	0.48	0.82	18	empty
2	195	0.48	0.75	22	empty
3	148	0.45	0.76	19	empty
4	96	0.38	0.76	17	empty
5	94	0.38	0.76	19	empty

Interfaces

1 interface between chains.

A–B · 809 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

6MC6 · Crystal structure of PprA filament from Deinococcus radiodurans · the same entry in another collection · chain A against A, TM-score 1.00
O32504 · AlphaFold monomer V2.0 prediction for DNA repair protein ppra (O32504) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O32504
Elsewhere: RCSB PDB 6MC6 · PDBe 6MC6 · UniProt O32504

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