MolNFT v1 · #156679 · protein

Crystal structure of muskmelon allergen cuc M 2

6MBX · Profilin: “Crystal structure of muskmelon allergen cuc M 2”. X-ray diffraction, 2 pockets (best druggability 0.66). MolNFT v1 #156679 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MBX
Type: protein
Length: 390 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Profilin
UniProt: Q5FX67
Pockets: 2 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Profilin	protein	130	27% helix, 32% strand	Q5FX67

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	514	0.66	0.77	45	empty
2	136	0.47	0.78	24	empty

Interfaces

3 interfaces between chains.

A–B · 624 Å² buried · 8 hydrogen bonds · protein-protein
B–C · 435 Å² buried · 3 hydrogen bonds · protein-protein
A–C · 70 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

6MBX · Crystal structure of muskmelon allergen cuc M 2 · the same entry in another collection · chain A against A, TM-score 1.00
Q5FX67 · AlphaFold monomer V2.0 prediction for profilin (Q5FX67) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5FX67
Elsewhere: RCSB PDB 6MBX · PDBe 6MBX · UniProt Q5FX67

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