MolNFT v1 · #156662 · protein
Human mcl-1 in complex with the designed peptide DM7
6MBE · Induced myeloid leukemia cell differentiation protein mcl- 1: “Human mcl-1 in complex with the designed peptide DM7”. X-ray diffraction, 1 ligand (CL). MolNFT v1 #156662 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6MBE
- Type
- protein
- Length
- 176 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Induced myeloid leukemia cell differentiation protein mcl- 1; DM7
- UniProt
- Q07820
- Ligands
- CL
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Induced myeloid leukemia cell differentiation protein mcl- 1 | protein | 154 | 76% helix, 0% strand | Q07820 |
| B | DM7 | protein | 22 | 77% helix, 0% strand | — |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 964 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 6MBE · Human Mcl-1 in complex with the designed peptide dM7 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07820
- Elsewhere: RCSB PDB 6MBE · PDBe 6MBE · UniProt Q07820
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.