MolNFT v1 · #156636 · protein
Crystal structure of deoxyuridine 5'-triphosphate nucleotidohydrolase from legionella pneumophila philadelphia 1 in complex with dump (deoxyuridine 5'-monophosphate)
6MAO: “Crystal structure of deoxyuridine 5'-triphosphate nucleotidohydrolase from legionella pneumophila…”. X-ray diffraction, 2 ligands (UMP, SO4), 1 pocket (best druggability 0.34). MolNFT v1 #156636 on GenesisL1: 3D structure, binding…
- PDB
- 6MAO
- Type
- protein
- Length
- 137 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- EC
- 3.6.1.23
- UniProt
- Q5ZSN0
- Ligands
- UMP, SO4
- Pockets
- 1 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 5% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23) | protein | 137 | 5% helix, 42% strand | Q5ZSN0 |
Ligands and binding sites
- UMP · 2'-deoxyuridine 5'-monophosphate · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.34 | 0.74 | 14 | empty |
Compared structures
- 6MAO · Crystal structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase from Legionella… · the same entry in another collection · chain A against A, TM-score 1.00
- Q5ZSN0 · AlphaFold monomer V2.0 prediction for deoxyuridine 5'-triphosphate nucleotidohydrolase… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZSN0
- Elsewhere: RCSB PDB 6MAO · PDBe 6MAO · UniProt Q5ZSN0
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