MolNFT v1 · #156633 · protein

Structure of human nocturnin C-terminal domain

6MAL: “Structure of human nocturnin C-terminal domain”. X-ray diffraction, 1 ligand (MG), 2 pockets (best druggability 0.63). MolNFT v1 #156633 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6MAL
Type: protein
Length: 303 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nocturnin
EC: 3.1.13.4
UniProt: Q9UK39
Ligands: MG
Pockets: 2 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nocturnin (EC 3.1.13.4)	protein	303	23% helix, 34% strand	Q9UK39

Ligands and binding sites

MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	301	0.63	0.80	32	MG
2	51	0.30	0.76	19	empty

Compared structures

6MAL · Structure of human Nocturnin C-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9UK39 · AlphaFold monomer V2.0 prediction for nocturnin (Q9UK39) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UK39
Elsewhere: RCSB PDB 6MAL · PDBe 6MAL · UniProt Q9UK39

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