MolNFT v1 · #156628 · protein
Native bbvci A2B2 tetramer at low resolution
6MAF · Bbvci endonuclease subunit 1: “Native bbvci A2B2 tetramer at low resolution”. X-ray diffraction, 20 pockets (best druggability 0.89). MolNFT v1 #156628 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6MAF
- Type
- protein
- Length
- 1,072 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bbvci endonuclease subunit 1; Bbvci endonuclease subunit 2
- UniProt
- Q5D6Y5, Q5D6Y4
- Pockets
- 20 · best druggability 0.89
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Bbvci endonuclease subunit 1 | protein | 259 | 40% helix, 19% strand | Q5D6Y5 |
| C, D | Bbvci endonuclease subunit 2 | protein | 277 | 45% helix, 26% strand | Q5D6Y4 |
Pockets
20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1079 | 0.89 | 0.91 | 114 | empty |
| 2 | 469 | 0.81 | 0.88 | 52 | empty |
| 3 | 464 | 0.80 | 0.87 | 52 | empty |
| 4 | 206 | 0.72 | 0.88 | 29 | empty |
| 5 | 114 | 0.69 | 0.91 | 23 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1884 Ų buried · 18 hydrogen bonds · protein-protein
- A–B · 885 Ų buried · 13 hydrogen bonds · protein-protein
- B–D · 681 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 669 Ų buried · 5 hydrogen bonds · protein-protein
- A–D · 665 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 6MAF · native BbvCI A2B2 tetramer at low resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5D6Y5
- Every structure of UniProt Q5D6Y4
- Elsewhere: RCSB PDB 6MAF · PDBe 6MAF · UniProt Q5D6Y5 · UniProt Q5D6Y4
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