MolNFT v1 · #156555 · protein

Structure of human CYP11B1 in complex with fadrozole

6M7X: “Structure of human CYP11B1 in complex with fadrozole”. X-ray diffraction, 2 ligands (JD7, HEM). MolNFT v1 #156555 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6M7X
Type: protein
Length: 924 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P15538
Ligands: JD7, HEM

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	463	—	P15538
B	—	protein	461	—	P15538

Ligands and binding sites

JD7 · 4-[(5S)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile · ligand · 2 copies · chains A, B
HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6M7X · Structure of human CYP11B1 in complex with fadrozole · the same entry in another collection · chain A against A, TM-score 1.00
P15538 · AlphaFold monomer V2.0 prediction for cytochrome P450 11B1, mitochondrial (P15538) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15538
Elsewhere: RCSB PDB 6M7X · PDBe 6M7X · UniProt P15538

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