MolNFT v1 · #156477 · protein

Crystal structure of 2019-ncov NSP7-NSP8C complex

6M5I · Non-structural protein 8: “Crystal structure of 2019-ncov NSP7-NSP8C complex”. X-ray diffraction, 1 pocket (best druggability 0.32). MolNFT v1 #156477 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6M5I
Type: protein
Length: 196 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Non-structural protein 8; Non-structural protein 7
UniProt: P0DTC1
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 2 distinct chains · 53% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Non-structural protein 8	protein	115	37% helix, 27% strand	P0DTC1
A	Non-structural protein 7	protein	81	74% helix, 0% strand	P0DTC1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.32	0.76	15	empty

Interfaces

1 interface between chains.

B–A · 1422 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

6M5I · Crystal structure of 2019-nCoV nsp7-nsp8c complex · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0DTC1
Elsewhere: RCSB PDB 6M5I · PDBe 6M5I · UniProt P0DTC1

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