MolNFT v1 · #156321 · DNA
Trimolecular G-quadruplex
6M05 · DNA (5'-D(*GP*TP*TP*AP*GP*G)-3'): “Trimolecular G-quadruplex”. Solution nmr, 1 pocket (best druggability 0.26). MolNFT v1 #156321 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6M05
- Type
- DNA
- Length
- 18 nucleotides
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (5'-D(*GP*TP*TP*AP*GP*G)-3')
- Pockets
- 1 · best druggability 0.26
Structure
solution nmr · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | DNA (5'-D(*GP*TP*TP*AP*GP*G)-3') | dna | 6 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.26 | 0.73 | 7 | empty |
Interfaces
3 interfaces between chains.
- A–C · 224 Ų buried · 13 hydrogen bonds · nucleic-nucleic
- A–B · 213 Ų buried · 7 hydrogen bonds · nucleic-nucleic
- B–C · 177 Ų buried · 8 hydrogen bonds · nucleic-nucleic
Compared structures
- 6M05 · Trimolecular G-quadruplex · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6M05 · PDBe 6M05
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