MolNFT v1 · #156299 · protein
Crystal structure of ALPHA/BETA hydrolase grgf from penicillium sp. SH18
6LZH: “Crystal structure of ALPHA/BETA hydrolase grgf from penicillium sp. SH18”. X-ray diffraction, 1 ligand (NA), 10 pockets (best druggability 0.75). MolNFT v1 #156299 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LZH
- Type
- protein
- Length
- 578 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Grgf
- Ligands
- NA
- Pockets
- 10 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Grgf | protein | 289 | 39% helix, 20% strand | — |
Ligands and binding sites
- NA · Sodium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.75 | 0.97 | 28 | NA |
| 2 | 78 | 0.74 | 0.97 | 20 | empty |
| 3 | 64 | 0.72 | 0.97 | 21 | empty |
| 4 | 70 | 0.69 | 0.95 | 28 | NA |
| 5 | 387 | 0.64 | 0.79 | 31 | empty |
Interfaces
1 interface between chains.
- A–B · 1781 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 6LZH · Crystal structure of Alpha/beta hydrolase GrgF from Penicillium sp. sh18 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6LZH · PDBe 6LZH
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.