MolNFT v1 · #156194 · protein
Structure of LPG2148/LPG2149 complex
6LW4 · Uncharacterized protein LPG2148: “Structure of LPG2148/LPG2149 complex”. X-ray diffraction, 4 pockets (best druggability 0.75). MolNFT v1 #156194 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LW4
- Type
- protein
- Length
- 489 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein LPG2148; Uncharacterized protein LPG2149
- UniProt
- Q5ZTL3, Q5ZTL2
- Pockets
- 4 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein LPG2148 | protein | 383 | 50% helix, 14% strand | Q5ZTL3 |
| B | Uncharacterized protein LPG2149 | protein | 106 | 67% helix, 0% strand | Q5ZTL2 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 343 | 0.75 | 0.86 | 41 | empty |
| 2 | 167 | 0.46 | 0.76 | 20 | empty |
| 3 | 61 | 0.31 | 0.75 | 11 | empty |
| 4 | 72 | 0.27 | 0.72 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1349 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 6LW4 · Structure of Lpg2148/Lpg2149 complex · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZTL3
- Every structure of UniProt Q5ZTL2
- Elsewhere: RCSB PDB 6LW4 · PDBe 6LW4 · UniProt Q5ZTL3 · UniProt Q5ZTL2
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