MolNFT v1 · #156087 · protein

Crystal straucture of USO1-1

6LST · Intracellular protein transport protein USO1: “Crystal straucture of USO1-1”. X-ray diffraction, 4 pockets (best druggability 0.70). MolNFT v1 #156087 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6LST
Type: protein
Length: 647 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Intracellular protein transport protein USO1
UniProt: P25386
Pockets: 4 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 68% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Intracellular protein transport protein USO1	protein	647	68% helix, 2% strand	P25386

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	701	0.70	0.77	65	empty
2	79	0.44	0.81	16	empty
3	95	0.36	0.74	21	empty
4	52	0.30	0.76	15	empty

Compared structures

6LST · Crystal straucture of Uso1-1 · the same entry in another collection · chain A against A, TM-score 1.00
P25386 · AlphaFold monomer V2.0 prediction for intracellular protein transport protein USO1… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25386
Elsewhere: RCSB PDB 6LST · PDBe 6LST · UniProt P25386

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