MolNFT v1 · #156065 · protein
Rod-shaped crystal of tmftn mutant-T4FY stimulited by PLL15
6LS0 · Ferritin: “Rod-shaped crystal of tmftn mutant-T4FY stimulited by PLL15”. X-ray diffraction, 1 ligand (FE), 5 pockets (best druggability 0.71). MolNFT v1 #156065 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LS0
- Type
- protein
- Length
- 651 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferritin
- EC
- 1.16.3.2
- UniProt
- Q9X0L2
- Ligands
- FE
- Pockets
- 5 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| H, A, B | Ferritin (EC 1.16.3.2) | protein | 163 | 77% helix, 1% strand | Q9X0L2 |
| C | Ferritin (EC 1.16.3.2) | protein | 162 | 79% helix, 0% strand | Q9X0L2 |
Ligands and binding sites
- FE · Fe (III) ion · metal · 7 copies · chains H, A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 856 | 0.71 | 0.76 | 65 | empty |
| 2 | 259 | 0.71 | 0.85 | 27 | empty |
| 3 | 125 | 0.42 | 0.76 | 20 | empty |
| 4 | 66 | 0.31 | 0.74 | 13 | empty |
| 5 | 53 | 0.29 | 0.75 | 16 | empty |
Interfaces
4 interfaces between chains.
- H–B · 1283 Ų buried · 24 hydrogen bonds · protein-protein
- H–A · 518 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 517 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 390 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 6LS0 · rod-shaped crystal of TmFtn mutant-T4FY stimulited by PLL15 · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X0L2
- Elsewhere: RCSB PDB 6LS0 · PDBe 6LS0 · UniProt Q9X0L2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.