MolNFT v1 · #156054 · protein
Crystal structure of isocitrate lyase (CAUR_3889) from chloroflexus aurantiacus in complex with manganese ion
6LRP: “Crystal structure of isocitrate lyase (CAUR_3889) from chloroflexus aurantiacus in complex with manganese ion”. X-ray diffraction, 1 ligand (P3G), 2 pockets (best druggability 0.31). MolNFT v1 #156054 on GenesisL1: 3D structure…
- PDB
- 6LRP
- Type
- protein
- Length
- 390 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isocitrate lyase
- UniProt
- A9WDE7
- Ligands
- P3G
- Pockets
- 2 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isocitrate lyase | protein | 390 | 51% helix, 13% strand | A9WDE7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 69 | 0.31 | 0.74 | 23 | empty |
| 2 | 81 | 0.28 | 0.71 | 21 | empty |
Compared structures
- 6LRP · Crystal structure of isocitrate lyase (Caur_3889) from Chloroflexus aurantiacus in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A9WDE7
- Elsewhere: RCSB PDB 6LRP · PDBe 6LRP · UniProt A9WDE7
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