MolNFT v1 · #155835 · protein

Crystal structure of human wild type TRIP13

6LK0 · Pachytene checkpoint protein 2 homolog: “Crystal structure of human wild type TRIP13”. X-ray diffraction, 6 pockets (best druggability 0.57). MolNFT v1 #155835 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6LK0
Type: protein
Length: 336 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pachytene checkpoint protein 2 homolog
UniProt: Q15645
Pockets: 6 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pachytene checkpoint protein 2 homolog	protein	336	45% helix, 18% strand	Q15645

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	152	0.57	0.82	25	empty
2	117	0.53	0.82	20	empty
3	135	0.47	0.78	24	empty
4	207	0.45	0.73	31	empty
5	59	0.33	0.77	14	empty

Compared structures

6LK0 · Crystal structure of human wild type TRIP13 · the same entry in another collection · chain A against A, TM-score 1.00
Q15645 · AlphaFold monomer V2.0 prediction for pachytene checkpoint protein 2 homolog (Q15645) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15645
Elsewhere: RCSB PDB 6LK0 · PDBe 6LK0 · UniProt Q15645

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