MolNFT v1 · #155469 · protein

Crystal structure of CYP97A3 mutant S290D/W300L/S304V

6L8I · Protein lutein deficient 5, chloroplastic: “Crystal structure of CYP97A3 mutant S290D/W300L/S304V”. X-ray diffraction, 1 ligand (HEM), 3 pockets (best druggability 0.85). MolNFT v1 #155469 on GenesisL1: 3D structure, binding sites…

PDB: 6L8I
Type: protein
Length: 439 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein lutein deficient 5, chloroplastic
EC: 1.14.-.-
UniProt: Q93VK5
Ligands: HEM
Pockets: 3 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 55% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein lutein deficient 5, chloroplastic (EC 1.14.-.-)	protein	439	55% helix, 11% strand	Q93VK5

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	639	0.85	0.89	75	HEM
2	149	0.53	0.80	27	empty
3	67	0.30	0.74	15	empty

Compared structures

6L8I · Crystal structure of CYP97A3 mutant S290D/W300L/S304V · the same entry in another collection · chain A against A, TM-score 1.00
Q93VK5 · AlphaFold monomer V2.0 prediction for protein lutein deficient 5, chloroplastic (Q93VK5) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q93VK5
Elsewhere: RCSB PDB 6L8I · PDBe 6L8I · UniProt Q93VK5

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