MolNFT v1 · #155430 · protein
Csgfg complex in curli biogenesis system
6L7A · Curli production ASSEMBLY/TRANSPORT protein csgg: “Csgfg complex in curli biogenesis system”. Electron microscopy, 20 pockets (best druggability 0.88). MolNFT v1 #155430 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6L7A
- Type
- protein
- Length
- 2,538 residues
- Chains
- 18
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Curli production ASSEMBLY/TRANSPORT protein csgg; Csgf
- UniProt
- A0A027ZN26, B2CY45
- Pockets
- 20 · best druggability 0.88
Structure
electron microscopy · 2 distinct chains · 28% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I | Curli production ASSEMBLY/TRANSPORT protein csgg | protein | 246 | 28% helix, 37% strand | A0A027ZN26 |
| J, K, L, M, N, O, P, Q, R | Csgf | protein | 36 | 33% helix, 0% strand | B2CY45 |
Pockets
20 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1176 | 0.88 | 0.90 | 223 | empty |
| 2 | 336 | 0.53 | 0.74 | 61 | empty |
| 3 | 125 | 0.53 | 0.81 | 19 | empty |
| 4 | 145 | 0.52 | 0.80 | 23 | empty |
| 5 | 140 | 0.51 | 0.80 | 29 | empty |
Interfaces
45 interfaces between chains.
- F–G · 2975 Ų buried · 39 hydrogen bonds · protein-protein
- A–B · 2971 Ų buried · 39 hydrogen bonds · protein-protein
- G–H · 2968 Ų buried · 40 hydrogen bonds · protein-protein
- A–I · 2967 Ų buried · 39 hydrogen bonds · protein-protein
- C–D · 2964 Ų buried · 39 hydrogen bonds · protein-protein
Compared structures
- 6L7A · CsgFG complex in Curli biogenesis system · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A027ZN26
- Every structure of UniProt B2CY45
- Elsewhere: RCSB PDB 6L7A · PDBe 6L7A · UniProt A0A027ZN26 · UniProt B2CY45
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