MolNFT v1 · #155301 · protein

Crystal structure of the epithelial cell transforming 2 (ECT2)

6L30 · Protein ECT2: “Crystal structure of the epithelial cell transforming 2 (ECT2)”. X-ray diffraction, 6 pockets (best druggability 0.54). MolNFT v1 #155301 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6L30
Type: protein
Length: 518 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein ECT2
UniProt: Q9H8V3
Pockets: 6 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein ECT2	protein	518	49% helix, 17% strand	Q9H8V3

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	230	0.54	0.77	26	empty
2	62	0.53	0.87	23	empty
3	170	0.43	0.74	21	empty
4	60	0.39	0.79	13	empty
5	72	0.36	0.77	16	empty

Compared structures

6L30 · Crystal structure of the epithelial cell transforming 2 (ECT2) · the same entry in another collection · chain A against A, TM-score 1.00
Q9H8V3 · AlphaFold monomer V2.0 prediction for protein ECT2 (Q9H8V3) · a predicted model of the same protein · chain A against A, TM-score 0.61

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H8V3
Elsewhere: RCSB PDB 6L30 · PDBe 6L30 · UniProt Q9H8V3

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