MolNFT v1 · #155196 · protein
Macrocyclization of an all-D linear peptide improves target affinity and imparts cellular activity: a novel stapled alpha-helical peptide modality
6KZU: “Macrocyclization of an all-D linear peptide improves target affinity and imparts cellular activity: a novel…”. X-ray diffraction, 1 ligand (2JN). MolNFT v1 #155196 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6KZU
- Type
- protein
- Length
- 94 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q00987
- Ligands
- 2JN
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 85 | — | Q00987 |
| B | — | protein | 9 | — | — |
Ligands and binding sites
- 2JN · 2-methyl-D-norleucine · ligand · 3 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6KZU · Macrocyclization of an all-D linear peptide improves target affinity and imparts cellular… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00987
- Elsewhere: RCSB PDB 6KZU · PDBe 6KZU · UniProt Q00987
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.