MolNFT v1 · #155170 · protein
Yebt domain 5-7
6KZ4 · Intermembrane transport protein yebt: “Yebt domain 5-7”. Electron microscopy, 20 pockets (best druggability 0.79). MolNFT v1 #155170 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6KZ4
- Type
- protein
- Length
- 2,196 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Intermembrane transport protein yebt
- UniProt
- P76272
- Pockets
- 20 · best druggability 0.79
Structure
electron microscopy · 1 distinct chain · 7% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E, F, C, D, A, B | Intermembrane transport protein yebt | protein | 366 | 7% helix, 36% strand | P76272 |
Pockets
20 pockets found on a 1 Å grid, 18 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 624 | 0.79 | 0.85 | 109 | empty |
| 2 | 1176 | 0.75 | 0.78 | 150 | empty |
| 3 | 331 | 0.72 | 0.84 | 56 | empty |
| 4 | 288 | 0.68 | 0.84 | 48 | empty |
| 5 | 257 | 0.68 | 0.84 | 34 | empty |
Interfaces
6 interfaces between chains.
- A–B · 2708 Ų buried · 32 hydrogen bonds · protein-protein
- C–D · 2706 Ų buried · 25 hydrogen bonds · protein-protein
- E–F · 2706 Ų buried · 24 hydrogen bonds · protein-protein
- E–D · 2224 Ų buried · 13 hydrogen bonds · protein-protein
- F–A · 2223 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P76272
- Elsewhere: RCSB PDB 6KZ4 · PDBe 6KZ4 · UniProt P76272
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