Crystal structure of GH30 xylanase B from talaromyces cellulolyticus expressed by pichia pastoris in complex with aldotriuronic acid

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 28% strand (DSSP).

Ligands and binding sites

• GCV · 4-O-methyl-alpha-D-glucopyranuronic acid · ligand · chains A
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 10 copies · chains A
• MAN · alpha-D-mannopyranose · sugar · 4 copies · chains A
• BMA · beta-D-mannopyranose · sugar · 3 copies · chains A
• XYP · beta-D-xylopyranose · sugar · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 5 glycan, 2 disulfide (N-glycosylation, disulfide).

Compared structures

• 6KRN · Crystal structure of GH30 xylanase B from Talaromyces cellulolyticus expressed by Pichia… · the same entry in another collection · chain A against A, TM-score 1.00
• P25501 · AlphaFold monomer V2.0 prediction for mating factor alpha (P25501) · a predicted model of the same protein · chain A against A, TM-score 0.11

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P25501
• Every structure of UniProt A0A4V8H018
• Elsewhere: RCSB PDB 6KRN · PDBe 6KRN · UniProt P25501 · UniProt A0A4V8H018