MolNFT v1 · #154933 · protein
Structure of the BETA2 adrenergic receptor in the full agonist bound state
6KR8 · Beta 2 adrenergic receptor: “Structure of the BETA2 adrenergic receptor in the full agonist bound state”. Solution nmr, 6 pockets (best druggability 0.76). MolNFT v1 #154933 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6KR8
- Type
- protein
- Length
- 312 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta 2 adrenergic receptor
- Pockets
- 6 · best druggability 0.76
Structure
solution nmr · 1 distinct chain · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta 2 adrenergic receptor | protein | 312 | 71% helix, 0% strand | — |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 369 | 0.76 | 0.86 | 54 | empty |
| 2 | 307 | 0.64 | 0.80 | 44 | empty |
| 3 | 118 | 0.61 | 0.86 | 20 | empty |
| 4 | 176 | 0.54 | 0.79 | 22 | empty |
| 5 | 63 | 0.32 | 0.76 | 15 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6KR8 · Structure of the beta2 adrenergic receptor in the full agonist bound state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6KR8 · PDBe 6KR8
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