MolNFT v1 · #154614 · protein
Bacterial cystathionine gamma-lyase mccb of staphylococcus aureus
6KGZ: “Bacterial cystathionine gamma-lyase mccb of staphylococcus aureus”. X-ray diffraction, 2 pockets (best druggability 0.67). MolNFT v1 #154614 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6KGZ
- Type
- protein
- Length
- 368 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cystathionine gamma-lyase
- EC
- 4.4.1.1
- UniProt
- A0A0H3JQ19
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cystathionine gamma-lyase (EC 4.4.1.1) | protein | 368 | 40% helix, 15% strand | A0A0H3JQ19 |
Ligands and binding sites
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 307 | 0.67 | 0.82 | 36 | TRS |
| 2 | 62 | 0.41 | 0.81 | 14 | empty |
Compared structures
- 6KGZ · bacterial cystathionine gamma-lyase MccB of Staphylococcus aureus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H3JQ19
- Elsewhere: RCSB PDB 6KGZ · PDBe 6KGZ · UniProt A0A0H3JQ19
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