MolNFT v1 · #154498 · protein
Structural and catalytic analysis of two diverse uridine phosphorylases in the oomycete phytophthora capsici.
6KD3: “Structural and catalytic analysis of two diverse uridine phosphorylases in the oomycete phytophthora capsici.”. X-ray diffraction, 5 pockets (best druggability 0.83). MolNFT v1 #154498 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6KD3
- Type
- protein
- Length
- 588 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uridine phosphorylase
- EC
- 2.4.2.3
- Pockets
- 5 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Uridine phosphorylase (EC 2.4.2.3) | protein | 294 | 30% helix, 17% strand | — |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 899 | 0.83 | 0.85 | 127 | empty |
| 2 | 430 | 0.72 | 0.83 | 45 | empty |
| 3 | 422 | 0.71 | 0.82 | 39 | empty |
| 4 | 65 | 0.36 | 0.77 | 18 | empty |
| 5 | 51 | 0.35 | 0.79 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 2397 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 6KD3 · Structural and catalytic analysis of two diverse uridine phosphorylases in the oomycete… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6KD3 · PDBe 6KD3
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