MolNFT v1 · #154193 · protein

Human galectin-14

6K2Y · Placental protein 13-like: “Human galectin-14”. X-ray diffraction, 1 pocket (best druggability 0.67). MolNFT v1 #154193 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6K2Y
Type: protein
Length: 275 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Placental protein 13-like
UniProt: Q8TCE9
Pockets: 1 · best druggability 0.67

Structure

x-ray diffraction · 2 distinct chains · 2% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Placental protein 13-like	protein	138	2% helix, 57% strand	Q8TCE9
B	Placental protein 13-like	protein	137	2% helix, 58% strand	Q8TCE9

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	228	0.67	0.84	31	empty

Interfaces

1 interface between chains.

A–B · 1888 Å² buried · 42 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6K2Y · Human Galectin-14 · the same entry in another collection · chain A against A, TM-score 1.00
Q8TCE9 · AlphaFold monomer V2.0 prediction for placental protein 13-like (Q8TCE9) · a predicted model of the same protein · chain B against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TCE9
Elsewhere: RCSB PDB 6K2Y · PDBe 6K2Y · UniProt Q8TCE9

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