MolNFT v1 · #154006 · protein
TEL1 kinase compact monomer
6JXA · SERINE/THREONINE-protein kinase TEL1: “TEL1 kinase compact monomer”. Electron microscopy, 20 pockets (best druggability 0.85). MolNFT v1 #154006 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6JXA
- Type
- protein
- Length
- 2,244 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/THREONINE-protein kinase TEL1
- EC
- 2.7.11.1
- UniProt
- P38110
- Pockets
- 20 · best druggability 0.85
Structure
electron microscopy · 1 distinct chain · 58% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase TEL1 (EC 2.7.11.1) | protein | 2244 | 58% helix, 0% strand | P38110 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 752 | 0.85 | 0.88 | 84 | empty |
| 2 | 356 | 0.82 | 0.91 | 39 | empty |
| 3 | 461 | 0.81 | 0.88 | 44 | empty |
| 4 | 597 | 0.81 | 0.86 | 80 | empty |
| 5 | 329 | 0.81 | 0.91 | 49 | empty |
Compared structures
- 6JXA · Tel1 kinase compact monomer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38110
- Elsewhere: RCSB PDB 6JXA · PDBe 6JXA · UniProt P38110
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.