MolNFT v1 · #15397 · protein
Structure and substrate of a histone H3 lysine methyltransferase from paramecium bursaria chlorella virus 1
1N3J: “Structure and substrate of a histone H3 lysine methyltransferase from paramecium bursaria chlorella virus 1”. Solution nmr, 4 pockets (best druggability 0.49). MolNFT v1 #15397 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1N3J
- Type
- protein
- Length
- 238 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Histone H3 lysine methyltransferase
- UniProt
- O41094
- Pockets
- 4 · best druggability 0.49
Structure
solution nmr · 1 distinct chain · 9% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Histone H3 lysine methyltransferase | protein | 119 | 9% helix, 33% strand | O41094 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.49 | 0.77 | 19 | empty |
| 2 | 146 | 0.46 | 0.77 | 20 | empty |
| 3 | 125 | 0.39 | 0.74 | 23 | empty |
| 4 | 52 | 0.34 | 0.79 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 643 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 1N3J · Structure and Substrate of a Histone H3 Lysine Methyltransferase from Paramecium Bursaria… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O41094
- Elsewhere: RCSB PDB 1N3J · PDBe 1N3J · UniProt O41094
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.