MolNFT v1 · #153855 · protein
Crystal structure of the H434A variant of the C-terminal domain of htaa from corynebacterium glutamicum
6JSC · Hypothetical membrane protein: “Crystal structure of the H434A variant of the C-terminal domain of htaa from corynebacterium glutamicum”. X-ray diffraction, 2 ligands (HEM, NA), 3 pockets (best druggability 0.50). MolNFT v1 #153855…
- PDB
- 6JSC
- Type
- protein
- Length
- 335 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical membrane protein
- UniProt
- Q8NTB9
- Ligands
- HEM, NA
- Pockets
- 3 · best druggability 0.50
Structure
x-ray diffraction · 2 distinct chains · 10% helix, 61% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical membrane protein | protein | 167 | 10% helix, 61% strand | Q8NTB9 |
| B | Hypothetical membrane protein | protein | 168 | 10% helix, 62% strand | Q8NTB9 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.50 | 0.82 | 16 | HEM |
| 2 | 84 | 0.50 | 0.82 | 16 | HEM |
| 3 | 152 | 0.45 | 0.76 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 559 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 6JSC · Crystal structure of the H434A variant of the C-terminal domain of HtaA from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NTB9
- Elsewhere: RCSB PDB 6JSC · PDBe 6JSC · UniProt Q8NTB9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.