MolNFT v1 · #153744 · protein

Crystal structure of mouse MXRA8

6JO7 · Matrix remodeling-associated protein 8: “Crystal structure of mouse MXRA8”. X-ray diffraction, 1 pocket (best druggability 0.61). MolNFT v1 #153744 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6JO7
Type: protein
Length: 504 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Matrix remodeling-associated protein 8
UniProt: Q9DBV4
Pockets: 1 · best druggability 0.61

Structure

x-ray diffraction · 2 distinct chains · 12% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Matrix remodeling-associated protein 8	protein	258	13% helix, 45% strand	Q9DBV4
B	Matrix remodeling-associated protein 8	protein	246	11% helix, 47% strand	Q9DBV4

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	321	0.61	0.78	37	empty

Interfaces

1 interface between chains.

A–B · 687 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

6JO7 · Crystal structure of mouse MXRA8 · the same entry in another collection · chain A against A, TM-score 1.00
Q9DBV4 · AlphaFold monomer V2.0 prediction for matrix remodeling-associated protein 8 (Q9DBV4) · a predicted model of the same protein · chain B against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9DBV4
Elsewhere: RCSB PDB 6JO7 · PDBe 6JO7 · UniProt Q9DBV4

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