MolNFT v1 · #153547 · protein
Crystal structure of biotin protein ligase from leishmania major in complex with biotinyl-5-AMP
6JHU · BIOTIN/LIPOATE protein ligase-like protein: “Crystal structure of biotin protein ligase from leishmania major in complex with biotinyl-5-AMP”. X-ray diffraction, 2 ligands (BT5, SO4), 3 pockets (best druggability 0.68). MolNFT v1…
- PDB
- 6JHU
- Type
- protein
- Length
- 247 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- BIOTIN/LIPOATE protein ligase-like protein
- EC
- 6.3.4.15
- UniProt
- Q4Q6F6
- Ligands
- BT5, SO4
- Pockets
- 3 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | BIOTIN/LIPOATE protein ligase-like protein (EC 6.3.4.15) | protein | 247 | 30% helix, 27% strand | Q4Q6F6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.68 | 0.91 | 20 | empty |
| 2 | 376 | 0.68 | 0.81 | 42 | BT5, SO4 |
| 3 | 93 | 0.32 | 0.72 | 19 | empty |
Compared structures
- 6JHU · Crystal Structure Of Biotin Protein Ligase From Leishmania Major in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4Q6F6
- Elsewhere: RCSB PDB 6JHU · PDBe 6JHU · UniProt Q4Q6F6
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