MolNFT v1 · #153532 · protein

Solution structure of ifn ALPHA8

6JHD · Interferon alpha-8: “Solution structure of ifn ALPHA8”. Solution nmr, 1 pocket (best druggability 0.63). MolNFT v1 #153532 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6JHD
Type: protein
Length: 166 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Interferon alpha-8
UniProt: P32881
Pockets: 1 · best druggability 0.63

Structure

solution nmr · 1 distinct chain · 63% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Interferon alpha-8	protein	166	63% helix, 0% strand	P32881

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	262	0.63	0.81	32	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

6JHD · Solution structure of IFN alpha8 · the same entry in another collection · chain A against A, TM-score 1.00
P32881 · AlphaFold monomer V2.0 prediction for interferon alpha-8 (P32881) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32881
Elsewhere: RCSB PDB 6JHD · PDBe 6JHD · UniProt P32881

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