MolNFT v1 · #153342 · protein
Structure of TPS1 apo structure
6JBI · Trehalose-6-phosphate synthase: “Structure of TPS1 apo structure”. X-ray diffraction, 9 pockets (best druggability 0.78). MolNFT v1 #153342 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6JBI
- Type
- protein
- Length
- 914 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trehalose-6-phosphate synthase
- EC
- 2.4.1.15
- UniProt
- G4NHF4
- Pockets
- 9 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Trehalose-6-phosphate synthase (EC 2.4.1.15) | protein | 457 | 46% helix, 18% strand | G4NHF4 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 742 | 0.78 | 0.82 | 73 | empty |
| 2 | 1141 | 0.75 | 0.78 | 82 | empty |
| 3 | 1021 | 0.75 | 0.77 | 67 | empty |
| 4 | 120 | 0.50 | 0.81 | 24 | empty |
| 5 | 109 | 0.50 | 0.81 | 25 | empty |
Interfaces
1 interface between chains.
- A–B · 1454 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 6JBI · Structure of Tps1 apo structure · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G4NHF4
- Elsewhere: RCSB PDB 6JBI · PDBe 6JBI · UniProt G4NHF4
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