MolNFT v1 · #153288 · protein
FNOBH+ACRIIC2
6J9L: “FNOBH+ACRIIC2”. X-ray diffraction, 2 pockets (best druggability 0.54). MolNFT v1 #153288 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6J9L
- Type
- protein
- Length
- 251 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ACRIIC2; Hnh endonuclease family protein
- UniProt
- A0A3E2QCQ3, A0A0B6KIH0
- Pockets
- 2 · best druggability 0.54
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ACRIIC2 | protein | 112 | 24% helix, 31% strand | A0A3E2QCQ3 |
| E | Hnh endonuclease family protein | protein | 27 | 85% helix, 0% strand | A0A0B6KIH0 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.54 | 0.82 | 31 | empty |
| 2 | 90 | 0.35 | 0.74 | 18 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1451 Ų buried · 24 hydrogen bonds · protein-protein
- B–E · 551 Ų buried · 16 hydrogen bonds · protein-protein
- A–E · 490 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 6J9L · FnoBH+AcrIIC2 · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A3E2QCQ3
- Every structure of UniProt A0A0B6KIH0
- Elsewhere: RCSB PDB 6J9L · PDBe 6J9L · UniProt A0A3E2QCQ3 · UniProt A0A0B6KIH0
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