MolNFT v1 · #153240 · protein
Crystal structure of toxin tglt (unusual type guanylyltransferase-like toxin, RV1045) mutant D82A from mycobacterium tuberculosis
6J7T: “Crystal structure of toxin tglt (unusual type guanylyltransferase-like toxin, RV1045) mutant D82A from…”. X-ray diffraction, 1 ligand (MG), 2 pockets (best druggability 0.69). MolNFT v1 #153240 on GenesisL1: 3D structure, binding…
- PDB
- 6J7T
- Type
- protein
- Length
- 290 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Guanylyltransferase-like toxin
- UniProt
- P96356
- Ligands
- MG
- Pockets
- 2 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanylyltransferase-like toxin | protein | 290 | 44% helix, 17% strand | P96356 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 483 | 0.69 | 0.80 | 40 | MG |
| 2 | 50 | 0.29 | 0.76 | 15 | empty |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 6J7T · Crystal structure of toxin TglT (unusual type guanylyltransferase-like toxin, Rv1045)… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P96356
- Elsewhere: RCSB PDB 6J7T · PDBe 6J7T · UniProt P96356
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