MolNFT v1 · #153217 · protein

Crystal structure of inia from mycobacterium smegmatis

6J73 · Isoniazid inducible gene protein inia: “Crystal structure of inia from mycobacterium smegmatis”. X-ray diffraction, 10 pockets (best druggability 0.76). MolNFT v1 #153217 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6J73
Type: protein
Length: 1,080 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Isoniazid inducible gene protein inia
UniProt: I7FE16
Pockets: 10 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 62% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Isoniazid inducible gene protein inia	protein	539	63% helix, 9% strand	I7FE16
B	Isoniazid inducible gene protein inia	protein	541	62% helix, 10% strand	I7FE16

Pockets

10 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1176	0.76	0.79	108	empty
2	1130	0.75	0.78	100	empty
3	319	0.59	0.77	35	empty
4	231	0.57	0.79	19	empty
5	120	0.56	0.83	23	empty

Interfaces

1 interface between chains.

A–B · 761 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

6J73 · Crystal structure of IniA from Mycobacterium smegmatis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt I7FE16
Elsewhere: RCSB PDB 6J73 · PDBe 6J73 · UniProt I7FE16

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.