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MolNFT v1 · #153207 · protein

Crystal structure of diamondback moth ryanodine receptor phosphorylation DOMAIN(2836-3050) mutant S2946D

6J6P: “Crystal structure of diamondback moth ryanodine receptor phosphorylation DOMAIN(2836-3050) mutant S2946D”. X-ray diffraction, 1 ligand (CL), 1 pocket (best druggability 0.50). MolNFT v1 #153207 on GenesisL1: 3D structure, binding…

PDB
6J6P
Type
protein
Length
192 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ryanodine receptor
UniProt
I3NWV8
Ligands
CL
Pockets
1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 7% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARyanodine receptorprotein19253% helix, 7% strandI3NWV8

Ligands and binding sites

  • CL · Chloride ion · ion · 2 copies · chains A
  • GOL · Glycerol · additive · 8 copies · chains A
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12440.500.7440EPE, GOL

Compared structures

  • 6J6P · Crystal structure of diamondback moth ryanodine receptor phosphorylation… · the same entry in another collection · chain A against A, TM-score 1.00

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