MolNFT v1 · #153119 · protein

Crystal structure of E. COLI peptide deformylase enzyme and chaperone trigger factor fitted into the cryo-EM density MAP of the complex

6J45: “Crystal structure of E. COLI peptide deformylase enzyme and chaperone trigger factor fitted into the cryo-EM…”. Electron microscopy, 3 pockets (best druggability 0.33). MolNFT v1 #153119 on GenesisL1: 3D structure, binding sites and…

PDB: 6J45
Type: protein
Length: 600 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Peptide deformylase; Trigger factor
EC: 3.5.1.88, 5.2.1.8
UniProt: F4VJS7, F4VAM2
Pockets: 3 · best druggability 0.33

Structure

electron microscopy · 2 distinct chains · 0% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
P	Peptide deformylase (EC 3.5.1.88)	protein	168	0% helix, 0% strand	F4VJS7
Q	Trigger factor (EC 5.2.1.8)	protein	432	0% helix, 0% strand	F4VAM2

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.33	0.73	23	empty
2	77	0.32	0.72	21	empty
3	51	0.27	0.72	14	empty

Compared structures

6J45 · Crystal structure of E. coli peptide deformylase enzyme and chaperone trigger factor… · the same entry in another collection · chain P against P, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F4VJS7
Every structure of UniProt F4VAM2
Elsewhere: RCSB PDB 6J45 · PDBe 6J45 · UniProt F4VJS7 · UniProt F4VAM2

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