MolNFT v1 · #153000 · protein
Crystal structure of human TERB2 and TERB1
6J07 · Telomere repeats-binding bouquet formation protein 2: “Crystal structure of human TERB2 and TERB1”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.57). MolNFT v1 #153000 on GenesisL1: 3D structure, binding sites…
- PDB
- 6J07
- Type
- protein
- Length
- 167 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Telomere repeats-binding bouquet formation protein 2; Telomere repeats-binding bouquet…
- UniProt
- Q8NHR7, Q8NA31
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomere repeats-binding bouquet formation protein 2 | protein | 107 | 37% helix, 14% strand | Q8NHR7 |
| B | Telomere repeats-binding bouquet formation protein 1 | protein | 60 | 50% helix, 0% strand | Q8NA31 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.57 | 0.83 | 24 | empty |
| 2 | 112 | 0.37 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1428 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 6J07 · Crystal structure of human TERB2 and TERB1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q8NHR7 · AlphaFold monomer V2.0 prediction for telomere repeats-binding bouquet formation protein… · a predicted model of the same protein · chain A against A, TM-score 0.86
- Q8NA31 · AlphaFold monomer V2.0 prediction for telomere repeats-binding bouquet formation protein… · a predicted model of the same protein · chain B against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NHR7
- Every structure of UniProt Q8NA31
- Elsewhere: RCSB PDB 6J07 · PDBe 6J07 · UniProt Q8NHR7 · UniProt Q8NA31
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