MolNFT v1 · #152968 · protein
Crystal structure of tagf from pseudomonas aeruginosa
6IZ8 · Type VI secretion-associated protein: “Crystal structure of tagf from pseudomonas aeruginosa”. X-ray diffraction, 6 pockets (best druggability 0.73). MolNFT v1 #152968 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6IZ8
- Type
- protein
- Length
- 895 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type VI secretion-associated protein
- UniProt
- A0A1Y3KGX5
- Pockets
- 6 · best druggability 0.73
Structure
x-ray diffraction · 5 distinct chains · 35% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Type VI secretion-associated protein | protein | 222 | 35% helix, 23% strand | A0A1Y3KGX5 |
| B | Type VI secretion-associated protein | protein | 215 | 35% helix, 23% strand | A0A1Y3KGX5 |
| C | Type VI secretion-associated protein | protein | 234 | 34% helix, 22% strand | A0A1Y3KGX5 |
| D | Type VI secretion-associated protein | protein | 212 | 37% helix, 25% strand | A0A1Y3KGX5 |
| F | Type VI secretion-associated protein | protein | 12 | 0% helix, 0% strand | A0A1Y3KGX5 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1056 | 0.73 | 0.77 | 97 | empty |
| 2 | 263 | 0.67 | 0.83 | 45 | empty |
| 3 | 425 | 0.65 | 0.78 | 56 | empty |
| 4 | 177 | 0.53 | 0.79 | 26 | empty |
| 5 | 59 | 0.46 | 0.83 | 15 | empty |
Interfaces
7 interfaces between chains.
- A–D · 1678 Ų buried · 22 hydrogen bonds · protein-protein
- B–C · 1642 Ų buried · 20 hydrogen bonds · protein-protein
- A–B · 828 Ų buried · 9 hydrogen bonds · protein-protein
- C–D · 733 Ų buried · 8 hydrogen bonds · protein-protein
- C–F · 449 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 6IZ8 · Crystal Structure of TagF from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1Y3KGX5
- Elsewhere: RCSB PDB 6IZ8 · PDBe 6IZ8 · UniProt A0A1Y3KGX5
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