MolNFT v1 · #152884 · protein

A designed domain swapped dimer

6IWJ · Archeal protein MK0293: “A designed domain swapped dimer”. Solution nmr, 1 pocket (best druggability 0.59). MolNFT v1 #152884 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6IWJ
Type: protein
Length: 158 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Archeal protein MK0293
UniProt: Q8TYK3
Pockets: 1 · best druggability 0.59

Structure

solution nmr · 1 distinct chain · 32% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Archeal protein MK0293	protein	79	32% helix, 37% strand	Q8TYK3

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	306	0.59	0.78	37	empty

Interfaces

1 interface between chains.

A–B · 2040 Å² buried · 33 hydrogen bonds · protein-protein

Compared structures

6IWJ · A designed domain swapped dimer · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TYK3
Elsewhere: RCSB PDB 6IWJ · PDBe 6IWJ · UniProt Q8TYK3

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