MolNFT v1 · #152786 · protein
Icosahedral asymmetric unit (iasu) model of the less refined, coarse part of fhv eluted particle
6ITF · Capsid protein beta: “Icosahedral asymmetric unit (iasu) model of the less refined, coarse part of fhv eluted particle”. Electron microscopy, 6 pockets (best druggability 0.71). MolNFT v1 #152786 on GenesisL1: 3D structure, binding…
- PDB
- 6ITF
- Type
- protein
- Length
- 519 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein beta
- EC
- 3.4.23.44
- UniProt
- P12870
- Pockets
- 6 · best druggability 0.71
Structure
electron microscopy · 3 distinct chains · 8% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Capsid protein beta (EC 3.4.23.44) | protein | 191 | 9% helix, 21% strand | P12870 |
| B | Capsid protein beta (EC 3.4.23.44) | protein | 168 | 10% helix, 14% strand | P12870 |
| C | Capsid protein beta (EC 3.4.23.44) | protein | 160 | 6% helix, 15% strand | P12870 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 730 | 0.71 | 0.78 | 81 | empty |
| 2 | 441 | 0.71 | 0.81 | 47 | empty |
| 3 | 567 | 0.69 | 0.78 | 71 | empty |
| 4 | 109 | 0.43 | 0.77 | 22 | empty |
| 5 | 136 | 0.42 | 0.74 | 23 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1047 Ų buried · 16 hydrogen bonds · protein-protein
- A–C · 811 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 611 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 6ITF · Icosahedral asymmetric unit (iASU) model of the less refined, coarse part of FHV eluted… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12870
- Elsewhere: RCSB PDB 6ITF · PDBe 6ITF · UniProt P12870
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