MolNFT v1 · #152758 · protein

MCD226

6ISA · CD226 antigen: “MCD226”. X-ray diffraction, 1 pocket (best druggability 0.50). MolNFT v1 #152758 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ISA
Type: protein
Length: 222 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CD226 antigen
UniProt: Q8K4F0
Pockets: 1 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CD226 antigen	protein	222	4% helix, 43% strand	Q8K4F0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.50	0.79	30	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

6ISA · mCD226 · the same entry in another collection · chain A against A, TM-score 1.00
Q8K4F0 · AlphaFold monomer V2.0 prediction for CD226 antigen (Q8K4F0) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8K4F0
Elsewhere: RCSB PDB 6ISA · PDBe 6ISA · UniProt Q8K4F0

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