Green fluorescent protein variant gfpuv with the modification to 6- hydroxynorleucine at the C-terminus

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 50% strand (DSSP).

Ligands and binding sites

• CRO · {2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A
• SO4 · Sulfate ion · ion · chains A
• MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 2 cofactor, 1 modified (chromophore, nonstandard).

Compared structures

• 6IR7 · Green fluorescent protein variant GFPuv with the modification to 6-hydroxynorleucine at… · the same entry in another collection · chain A against A, TM-score 1.00
• P42212 · AlphaFold monomer V2.0 prediction for green fluorescent protein (P42212) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P42212
• Elsewhere: RCSB PDB 6IR7 · PDBe 6IR7 · UniProt P42212