MolNFT v1 · #152714 · protein
High resolution structure of bilirubin oxidase from myrothecium verrucaria - wild type
6IQZ: “High resolution structure of bilirubin oxidase from myrothecium verrucaria - wild type”. X-ray diffraction, 3 ligands (NAG, MAN, CU), 2 pockets (best druggability 0.49). MolNFT v1 #152714 on GenesisL1: 3D structure, binding sites…
- PDB
- 6IQZ
- Type
- protein
- Length
- 535 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bilirubin oxidase
- EC
- 1.3.3.5
- UniProt
- Q12737
- Ligands
- NAG, MAN, CU
- Pockets
- 2 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 11% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bilirubin oxidase (EC 1.3.3.5) | protein | 535 | 11% helix, 40% strand | Q12737 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A
- MAN · alpha-D-mannopyranose · sugar
- CU · Copper (II) ion · metal · 4 copies · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 99 | 0.49 | 0.81 | 23 | empty |
| 2 | 127 | 0.46 | 0.78 | 19 | empty |
Modifications
Observed in the structure: 2 glycan (N-glycosylation).
Compared structures
- 6IQZ · High resolution structure of bilirubin oxidase from Myrothecium verrucaria - wild type · the same entry in another collection · chain A against A, TM-score 1.00
- Q12737 · AlphaFold monomer V2.0 prediction for bilirubin oxidase (Q12737) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12737
- Elsewhere: RCSB PDB 6IQZ · PDBe 6IQZ · UniProt Q12737
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.