MolNFT v1 · #152631 · protein

Silver-bound glyceraldehyde-3-phosphate dehydrogenase a at non- catalytic site

6IO6: “Silver-bound glyceraldehyde-3-phosphate dehydrogenase a at non- catalytic site”. X-ray diffraction, 1 ligand (AG), 2 pockets (best druggability 0.57). MolNFT v1 #152631 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6IO6
Type: protein
Length: 329 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glyceraldehyde-3-phosphate dehydrogenase a
EC: 1.2.1.12
UniProt: P0A9B2
Ligands: AG
Pockets: 2 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glyceraldehyde-3-phosphate dehydrogenase a (EC 1.2.1.12)	protein	329	30% helix, 27% strand	P0A9B2

Ligands and binding sites

AG · Silver ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	373	0.57	0.75	39	empty
2	50	0.35	0.79	21	empty

Compared structures

6IO6 · Silver-bound Glyceraldehyde-3-phosphate dehydrogenase A at non-catalytic site · the same entry in another collection · chain A against A, TM-score 1.00
P0A9B2 · AlphaFold monomer V2.0 prediction for glyceraldehyde-3-phosphate dehydrogenase a (P0A9B2) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A9B2
Elsewhere: RCSB PDB 6IO6 · PDBe 6IO6 · UniProt P0A9B2

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