MolNFT v1 · #152427 · protein

Crystal structure of phosphite dehydrogenase mutant I151R/P176E from ralstonia sp. 4506

6IH4: “Crystal structure of phosphite dehydrogenase mutant I151R/P176E from ralstonia sp. 4506”. X-ray diffraction, 5 pockets (best druggability 0.85). MolNFT v1 #152427 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6IH4
Type: protein
Length: 657 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphite dehydrogenase
UniProt: G4XDR8
Pockets: 5 · best druggability 0.85

Structure

x-ray diffraction · 2 distinct chains · 38% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphite dehydrogenase	protein	329	39% helix, 16% strand	G4XDR8
B	Phosphite dehydrogenase	protein	328	38% helix, 16% strand	G4XDR8

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	802	0.85	0.87	96	empty
2	624	0.77	0.83	50	empty
3	126	0.62	0.86	28	empty
4	115	0.50	0.80	24	empty
5	53	0.38	0.81	18	empty

Interfaces

1 interface between chains.

A–B · 1260 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

6IH4 · Crystal structure of Phosphite Dehydrogenase mutant I151R/P176E from Ralstonia sp. 4506 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G4XDR8
Elsewhere: RCSB PDB 6IH4 · PDBe 6IH4 · UniProt G4XDR8

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