MolNFT v1 · #15237 · protein

High resolution X-ray structures of pig metmyoglobin and two CD3 mutants MB(LYS45-> arg) and MB(LYS45-> ser)

1MYH: “High resolution X-ray structures of pig metmyoglobin and two CD3 mutants MB(LYS45-> arg) and MB(LYS45-> ser)”. X-ray diffraction, 2 ligands (HEM, SO4), 2 pockets (best druggability 0.71). MolNFT v1 #15237 on GenesisL1: 3D structure…

PDB: 1MYH
Type: protein
Length: 306 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myoglobin
UniProt: P02189
Ligands: HEM, SO4
Pockets: 2 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Myoglobin	protein	153	76% helix, 0% strand	P02189

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A, B
SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	194	0.71	0.87	23	HEM
2	181	0.71	0.87	24	HEM

Compared structures

1MYH · High resolution X-ray structures of pig metmyoglobin and two CD3 mutants MB(LYS45-> arg)… · the same entry in another collection · chain A against A, TM-score 1.00
P02189 · AlphaFold monomer V2.0 prediction for myoglobin (P02189) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02189
Elsewhere: RCSB PDB 1MYH · PDBe 1MYH · UniProt P02189

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