MolNFT v1 · #152204 · protein
Stod is a novel salmonella typhi type III secretion system E3 ubiquitin ligase effector
6IAI · Protein of uncharacterized function (DUF1076): “Stod is a novel salmonella typhi type III secretion system E3 ubiquitin ligase effector”. X-ray diffraction, 4 pockets (best druggability 0.71). MolNFT v1 #152204 on GenesisL1: 3D…
- PDB
- 6IAI
- Type
- protein
- Length
- 429 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein of uncharacterized function (DUF1076)
- UniProt
- Q8Z7T2
- Pockets
- 4 · best druggability 0.71
Structure
x-ray diffraction · 3 distinct chains · 32% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein of uncharacterized function (DUF1076) | protein | 107 | 34% helix, 24% strand | Q8Z7T2 |
| B, C | Protein of uncharacterized function (DUF1076) | protein | 108 | 32% helix, 24% strand | Q8Z7T2 |
| D | Protein of uncharacterized function (DUF1076) | protein | 106 | 30% helix, 25% strand | Q8Z7T2 |
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 263 | 0.71 | 0.86 | 38 | empty |
| 2 | 315 | 0.71 | 0.84 | 37 | empty |
| 3 | 429 | 0.62 | 0.77 | 74 | empty |
| 4 | 156 | 0.52 | 0.79 | 28 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1228 Ų buried · 10 hydrogen bonds · protein-protein
- A–B · 1171 Ų buried · 10 hydrogen bonds · protein-protein
- A–D · 520 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 515 Ų buried · 9 hydrogen bonds · protein-protein
- B–D · 371 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6IAI · StoD is a novel Salmonella Typhi type III secretion system E3 ubiquitin ligase effector · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8Z7T2
- Elsewhere: RCSB PDB 6IAI · PDBe 6IAI · UniProt Q8Z7T2
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