MolNFT v1 · #151964 · protein
Crystal structure of CPIZZA6-ayw, a circularly permuted designer protein
6I3B: “Crystal structure of CPIZZA6-ayw, a circularly permuted designer protein”. X-ray diffraction, 5 pockets (best druggability 0.80). MolNFT v1 #151964 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6I3B
- Type
- protein
- Length
- 504 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CPIZZA6-ayw
- Pockets
- 5 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | CPIZZA6-ayw | protein | 252 | 7% helix, 39% strand | — |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 682 | 0.80 | 0.84 | 78 | empty |
| 2 | 590 | 0.78 | 0.85 | 64 | empty |
| 3 | 160 | 0.46 | 0.77 | 24 | empty |
| 4 | 64 | 0.29 | 0.74 | 23 | empty |
| 5 | 50 | 0.27 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 335 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6I3B · Crystal structure of cPizza6-AYW, a circularly permuted designer protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6I3B · PDBe 6I3B
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